null

SMILES: COC(=O)c1cc(Br)ccc1Cn1c(=O)n(C)c2nc(N3CCC[C@@H](N)C3)n(CC#CC)c2c1=O

InChI Key: InChIKey=MFPOWIWYYFVDCZ-QGZVFWFLSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50516912   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Dipeptidyl peptidase 8 (Homo sapiens (Human))	BDBM50516912 (CHEMBL4465374) Show SMILES COC(=O)c1cc(Br)ccc1Cn1c(=O)n(C)c2nc(N3CCC[C@@H](N)C3)n(CC#CC)c2c1=O |r| Show InChI InChI=1S/C24H27BrN6O4/c1-4-5-11-30-19-20(27-23(30)29-10-6-7-17(26)14-29)28(2)24(34)31(21(19)32)13-15-8-9-16(25)12-18(15)22(33)35-3/h8-9,12,17H,6-7,10-11,13-14,26H2,1-3H3/t17-/m1/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Guangxi Medical University Curated by ChEMBL					Assay Description Inhibition of DPP8 (unknown origin) using Gly-Pro-AMC as substrate preincubated for 15 mins followed by substrate addition measured at 60 secs interv...				Eur J Med Chem 180: 509-523 (2019) Article DOI: 10.1016/j.ejmech.2019.07.045
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 9 (Homo sapiens (Human))	BDBM50516912 (CHEMBL4465374) Show SMILES COC(=O)c1cc(Br)ccc1Cn1c(=O)n(C)c2nc(N3CCC[C@@H](N)C3)n(CC#CC)c2c1=O |r| Show InChI InChI=1S/C24H27BrN6O4/c1-4-5-11-30-19-20(27-23(30)29-10-6-7-17(26)14-29)28(2)24(34)31(21(19)32)13-15-8-9-16(25)12-18(15)22(33)35-3/h8-9,12,17H,6-7,10-11,13-14,26H2,1-3H3/t17-/m1/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Guangxi Medical University Curated by ChEMBL					Assay Description Inhibition of DPP9 (unknown origin) using Gly-Pro-AMC as substrate preincubated for 15 mins followed by substrate addition measured at 60 secs interv...				Eur J Med Chem 180: 509-523 (2019) Article DOI: 10.1016/j.ejmech.2019.07.045
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 4 (Homo sapiens (Human))	BDBM50516912 (CHEMBL4465374) Show SMILES COC(=O)c1cc(Br)ccc1Cn1c(=O)n(C)c2nc(N3CCC[C@@H](N)C3)n(CC#CC)c2c1=O |r| Show InChI InChI=1S/C24H27BrN6O4/c1-4-5-11-30-19-20(27-23(30)29-10-6-7-17(26)14-29)28(2)24(34)31(21(19)32)13-15-8-9-16(25)12-18(15)22(33)35-3/h8-9,12,17H,6-7,10-11,13-14,26H2,1-3H3/t17-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	22	n/a	n/a	n/a	n/a	n/a	n/a
Guangxi Medical University Curated by ChEMBL					Assay Description Inhibition of recombinant human DPP4 expressed in baculovirus infected Sf9 insect cells using Gly-Pro-AMC as substrate preincubated for 15 mins follo...				Eur J Med Chem 180: 509-523 (2019) Article DOI: 10.1016/j.ejmech.2019.07.045
					More data for this Ligand-Target Pair