null

SMILES: COc1ccc(CN2CCC(=CC2)c2c[nH]c3ccc(OC)cc23)cc1

InChI Key: InChIKey=CXNXVMOAPQHKNR-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50517005   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM50517005 (CHEMBL4449936) Show SMILES COc1ccc(CN2CCC(=CC2)c2c[nH]c3ccc(OC)cc23)cc1 |c:10| Show InChI InChI=1S/C22H24N2O2/c1-25-18-5-3-16(4-6-18)15-24-11-9-17(10-12-24)21-14-23-22-8-7-19(26-2)13-20(21)22/h3-9,13-14,23H,10-12,15H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	134	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Medical University of Lublin Curated by ChEMBL					Assay Description Displacement of [3H]8-OH-DPAT from human 5HT1A receptor expressed in HEK293 cell membranes measured after 120 mins				Eur J Med Chem 180: 673-689 (2019) Article DOI: 10.1016/j.ejmech.2019.07.050
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50517005 (CHEMBL4449936) Show SMILES COc1ccc(CN2CCC(=CC2)c2c[nH]c3ccc(OC)cc23)cc1 |c:10| Show InChI InChI=1S/C22H24N2O2/c1-25-18-5-3-16(4-6-18)15-24-11-9-17(10-12-24)21-14-23-22-8-7-19(26-2)13-20(21)22/h3-9,13-14,23H,10-12,15H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	148	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Medical University of Lublin Curated by ChEMBL					Assay Description Displacement of [3H]Spiperone from human D2S receptor expressed in CHOK1 cell membranes measured after 120 mins				Eur J Med Chem 180: 673-689 (2019) Article DOI: 10.1016/j.ejmech.2019.07.050
					More data for this Ligand-Target Pair