BDBM50518679 CHEMBL4468962

SMILES: ONC(=O)CSc1nnc(Br)n1Cc1ccc(Br)c2ccccc12

InChI Key: InChIKey=YFRZVJXSLJRGCQ-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50518679   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Solute carrier family 22 member 12 (Homo sapiens (Human))	BDBM50518679 (CHEMBL4468962) Show SMILES ONC(=O)CSc1nnc(Br)n1Cc1ccc(Br)c2ccccc12 Show InChI InChI=1S/C15H12Br2N4O2S/c16-12-6-5-9(10-3-1-2-4-11(10)12)7-21-14(17)18-19-15(21)24-8-13(22)20-23/h1-6,23H,7-8H2,(H,20,22)	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	640	n/a	n/a	n/a	n/a	n/a	n/a
Tianjin Medical University Curated by ChEMBL					Assay Description Inhibition of human URAT1 expressed in HEK293 cells assessed as reduction in [8-14C]uric acid uptake				Bioorg Med Chem Lett 29: 383-388 (2019) Article DOI: 10.1016/j.bmcl.2018.12.036
					More data for this Ligand-Target Pair