BDBM50520100 CHEMBL4576681

SMILES: C\C=C\c1nnn(Cc2ccc(cc2)C(F)(F)F)c1C(=O)NC1(CC1)c1ccc(cc1)C(O)=O

InChI Key: InChIKey=ZOWOIFCPAIVCHT-NSCUHMNNSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50520100   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Prostanoid EP4 receptor (Mus musculus (Mouse))	BDBM50520100 (CHEMBL4576681) Show SMILES C\C=C\c1nnn(Cc2ccc(cc2)C(F)(F)F)c1C(=O)NC1(CC1)c1ccc(cc1)C(O)=O Show InChI InChI=1S/C24H21F3N4O3/c1-2-3-19-20(31(30-29-19)14-15-4-8-18(9-5-15)24(25,26)27)21(32)28-23(12-13-23)17-10-6-16(7-11-17)22(33)34/h2-11H,12-14H2,1H3,(H,28,32)(H,33,34)/b3-2+	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	34	n/a	n/a	n/a	n/a	n/a	n/a
East China Normal University Curated by ChEMBL					Assay Description Antagonist activity at mouse EP4 expressed in CHO cells coexpressing G16-alpha assessed as intracellular calcium flux preincubated for 15 mins follow...				J Med Chem 63: 569-590 (2020) Article DOI: 10.1021/acs.jmedchem.9b01269
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor (Homo sapiens (Human))	BDBM50520100 (CHEMBL4576681) Show SMILES C\C=C\c1nnn(Cc2ccc(cc2)C(F)(F)F)c1C(=O)NC1(CC1)c1ccc(cc1)C(O)=O Show InChI InChI=1S/C24H21F3N4O3/c1-2-3-19-20(31(30-29-19)14-15-4-8-18(9-5-15)24(25,26)27)21(32)28-23(12-13-23)17-10-6-16(7-11-17)22(33)34/h2-11H,12-14H2,1H3,(H,28,32)(H,33,34)/b3-2+	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	14	n/a	n/a	n/a	n/a	n/a	n/a
East China Normal University Curated by ChEMBL					Assay Description Antagonist activity at human EP4 expressed in CHO cells coexpressing G16-alpha assessed as intracellular calcium flux preincubated for 15 mins follow...				J Med Chem 63: 569-590 (2020) Article DOI: 10.1021/acs.jmedchem.9b01269
					More data for this Ligand-Target Pair