BDBM50522196 CHEMBL4589970

SMILES: Cc1ccc(cc1)-c1nc2Oc3c(C)cccc3Cc2c(SCC(=O)Nc2ccccc2)n1

InChI Key: InChIKey=NHNHHFZWGQRDGB-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50522196   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Uridine-cytidine kinase 2 (Homo sapiens)	BDBM50522196 (CHEMBL4589970) Show SMILES Cc1ccc(cc1)-c1nc2Oc3c(C)cccc3Cc2c(SCC(=O)Nc2ccccc2)n1 Show InChI InChI=1S/C27H23N3O2S/c1-17-11-13-19(14-12-17)25-29-26-22(15-20-8-6-7-18(2)24(20)32-26)27(30-25)33-16-23(31)28-21-9-4-3-5-10-21/h3-14H,15-16H2,1-2H3,(H,28,31)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.68E+4	n/a	n/a	n/a	n/a	n/a	n/a
Stanford University Curated by ChEMBL					Assay Description Inhibition of C-terminally His6-tagged human UCK2 expressed in Escherichia coli BL21(DE3) cells incubated for 15 mins before ATP addition and measure...				Bioorg Med Chem Lett 29: 2559-2564 (2019) Article DOI: 10.1016/j.bmcl.2019.08.010
					More data for this Ligand-Target Pair