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SMILES: FC(F)(F)C1(NC(Nc2ccc(Cl)c(Cl)c2)=Nc2ccc(Cl)cc12)C#CC1CC1

InChI Key: InChIKey=RVBDITSUSNBLOS-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50524503   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Reverse transcriptase


(Human immunodeficiency virus 1)		BDBM50524503
PNG
(CHEMBL4555651)
Show SMILES FC(F)(F)C1(NC(Nc2ccc(Cl)c(Cl)c2)=Nc2ccc(Cl)cc12)C#CC1CC1 |c:16|
Show InChI InChI=1S/C20H13Cl3F3N3/c21-12-3-6-17-14(9-12)19(20(24,25)26,8-7-11-1-2-11)29-18(28-17)27-13-4-5-15(22)16(23)10-13/h3-6,9-11H,1-2H2,(H2,27,28,29)
PDB
MMDB

UniProtKB/TrEMBL

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 3.70n/an/an/an/an/an/a



Fudan University

Curated by ChEMBL


Assay Description
Inhibition of recombinant wild-type HIV1 3B reverse transcriptase assessed as reduction in biotin-dUTP incorporation using poly(rA)/oligo(dT)16 as te...

Eur J Med Chem 176: 11-20 (2019)


Article DOI: 10.1016/j.ejmech.2019.05.011
BindingDB Entry DOI: 10.7270/Q2F47SJC
More data for this
Ligand-Target Pair