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SMILES: OC(C1COC(=O)C1=C)c1cn(Cc2ccc(Cl)cc2)c2ccc(Cl)cc12

InChI Key: InChIKey=GPJNTPRAIVNMNT-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50524613   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Lysine-specific histone demethylase 1A


(Homo sapiens (Human))		BDBM50524613
PNG
(CHEMBL4517041)
Show SMILES OC(C1COC(=O)C1=C)c1cn(Cc2ccc(Cl)cc2)c2ccc(Cl)cc12
Show InChI InChI=1S/C21H17Cl2NO3/c1-12-18(11-27-21(12)26)20(25)17-10-24(9-13-2-4-14(22)5-3-13)19-7-6-15(23)8-16(17)19/h2-8,10,18,20,25H,1,9,11H2
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n/an/a>1.00E+4n/an/an/an/an/an/a



Zhengzhou University

Curated by ChEMBL


Assay Description
Inhibition of recombinant LSD1 (unknown origin) (catalytic domain 157 to 852 residues) expressed in Escherichia coli BL21 using H3K4me1 as substrate ...

Eur J Med Chem 175: 357-372 (2019)


Article DOI: 10.1016/j.ejmech.2019.04.065
More data for this
Ligand-Target Pair