BDBM50525303 CHEMBL4546923

SMILES: COc1cc(ccc1Nc1ccc(N2CCCC2)c(Oc2cccc(NC(=O)C=C)c2)n1)N1CCN(C)CC1

InChI Key: InChIKey=WOMLNSKRAQZIPG-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50525303   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Dipeptidyl peptidase I (Homo sapiens (Human))	BDBM50525303 (CHEMBL4546923) Show SMILES COc1cc(ccc1Nc1ccc(N2CCCC2)c(Oc2cccc(NC(=O)C=C)c2)n1)N1CCN(C)CC1 Show InChI InChI=1S/C30H36N6O3/c1-4-29(37)31-22-8-7-9-24(20-22)39-30-26(36-14-5-6-15-36)12-13-28(33-30)32-25-11-10-23(21-27(25)38-3)35-18-16-34(2)17-19-35/h4,7-13,20-21H,1,5-6,14-19H2,2-3H3,(H,31,37)(H,32,33)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	175	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Biological Sciences (NIBS) Curated by ChEMBL					Assay Description Inhibition of CatL-activated recombinant human C-terminal His10-tagged cathepsin C (25 to 463 residues) expressed in mouse myeloma cells using Gly-Ph...				J Med Chem 62: 5901-5919 (2019) Article DOI: 10.1021/acs.jmedchem.9b00631
					More data for this Ligand-Target Pair