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SMILES: CN(C)c1ccc(cn1)-c1nc2cc([125I])ccc2o1

InChI Key: InChIKey=QFXSFMXKGHWKFO-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50528756   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Amyloid-beta precursor protein


(Homo sapiens (Human))		BDBM50528756
PNG
(CHEMBL4470128)
Show SMILES CN(C)c1ccc(cn1)-c1nc2cc([125I])ccc2o1
Show InChI InChI=1S/C14H12IN3O/c1-18(2)13-6-3-9(8-16-13)14-17-11-7-10(15)4-5-12(11)19-14/h3-8H,1-2H3
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MMDB

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PubMed
 6.90n/an/an/an/an/an/an/an/a



Indian Institute of Technology (Banaras Hindu University)

Curated by ChEMBL


Assay Description
Displacement of [125I]IMPY from human amyloid beta(1-42) aggregates incubated for 3 hrs by gamma counting analysis

Eur J Med Chem 182: (2019)


Article DOI: 10.1016/j.ejmech.2019.111613
More data for this
Ligand-Target Pair