BDBM50530119 CHEMBL4449438

SMILES: CC(C)C[C@@H]1NC(=O)[C@H](C)NC(=O)[C@@H]2CCCN2C(=O)[C@H]2CCCN2C(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(O)=O)NC(=O)CNC(=O)[C@H](CCCNC(N)=N)NC1=O

InChI Key: InChIKey=WEVPEJCRRVAGCF-FAFIDUEOSA-N

Data: 4 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50530119   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
ITGAV/ITGB8 (Homo sapiens (Human))	BDBM50530119 (CHEMBL4449438) Show SMILES CC(C)C[C@@H]1NC(=O)[C@H](C)NC(=O)[C@@H]2CCCN2C(=O)[C@H]2CCCN2C(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(O)=O)NC(=O)CNC(=O)[C@H](CCCNC(N)=N)NC1=O |r| Show InChI InChI=1S/C37H61N11O10/c1-19(2)15-23-32(54)44-22(9-6-12-40-37(38)39)31(53)41-18-28(49)43-24(17-29(50)51)33(55)46-25(16-20(3)4)35(57)48-14-8-11-27(48)36(58)47-13-7-10-26(47)34(56)42-21(5)30(52)45-23/h19-27H,6-18H2,1-5H3,(H,41,53)(H,42,56)(H,43,49)(H,44,54)(H,45,52)(H,46,55)(H,50,51)(H4,38,39,40)/t21-,22-,23-,24-,25-,26-,27+/m0/s1	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.30	n/a	n/a	n/a	n/a	n/a	n/a
Technische Universit£t M£nchen Curated by ChEMBL					Assay Description Inhibition of LAP binding to human integrin alphavbeta8 receptor after 1 hr by solid-phase binding assay				J Med Chem 62: 2024-2037 (2019) Article DOI: 10.1021/acs.jmedchem.8b01588
					More data for this Ligand-Target Pair
ITGAV/ITGB6 (Homo sapiens (Human))	BDBM50530119 (CHEMBL4449438) Show SMILES CC(C)C[C@@H]1NC(=O)[C@H](C)NC(=O)[C@@H]2CCCN2C(=O)[C@H]2CCCN2C(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(O)=O)NC(=O)CNC(=O)[C@H](CCCNC(N)=N)NC1=O |r| Show InChI InChI=1S/C37H61N11O10/c1-19(2)15-23-32(54)44-22(9-6-12-40-37(38)39)31(53)41-18-28(49)43-24(17-29(50)51)33(55)46-25(16-20(3)4)35(57)48-14-8-11-27(48)36(58)47-13-7-10-26(47)34(56)42-21(5)30(52)45-23/h19-27H,6-18H2,1-5H3,(H,41,53)(H,42,56)(H,43,49)(H,44,54)(H,45,52)(H,46,55)(H,50,51)(H4,38,39,40)/t21-,22-,23-,24-,25-,26-,27+/m0/s1	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	32	n/a	n/a	n/a	n/a	n/a	n/a
Technische Universit£t M£nchen Curated by ChEMBL					Assay Description Inhibition of LAP binding to human integrin alphavbeta6 receptor after 1 hr by solid-phase binding assay				J Med Chem 62: 2024-2037 (2019) Article DOI: 10.1021/acs.jmedchem.8b01588
					More data for this Ligand-Target Pair
ITGAV/ITGB8 (Homo sapiens (Human))	BDBM50530119 (CHEMBL4449438) Show SMILES CC(C)C[C@@H]1NC(=O)[C@H](C)NC(=O)[C@@H]2CCCN2C(=O)[C@H]2CCCN2C(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(O)=O)NC(=O)CNC(=O)[C@H](CCCNC(N)=N)NC1=O |r| Show InChI InChI=1S/C37H61N11O10/c1-19(2)15-23-32(54)44-22(9-6-12-40-37(38)39)31(53)41-18-28(49)43-24(17-29(50)51)33(55)46-25(16-20(3)4)35(57)48-14-8-11-27(48)36(58)47-13-7-10-26(47)34(56)42-21(5)30(52)45-23/h19-27H,6-18H2,1-5H3,(H,41,53)(H,42,56)(H,43,49)(H,44,54)(H,45,52)(H,46,55)(H,50,51)(H4,38,39,40)/t21-,22-,23-,24-,25-,26-,27+/m0/s1	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.30	n/a	n/a	n/a	n/a	n/a	n/a
Technische Universit£t M£nchen Curated by ChEMBL					Assay Description Inhibition of LAP binding to human integrin alphavbeta8 receptor after 1 hr by solid-phase binding assay				J Med Chem 62: 2024-2037 (2019) Article DOI: 10.1021/acs.jmedchem.8b01588
					More data for this Ligand-Target Pair
ITGAV/ITGB6 (Homo sapiens (Human))	BDBM50530119 (CHEMBL4449438) Show SMILES CC(C)C[C@@H]1NC(=O)[C@H](C)NC(=O)[C@@H]2CCCN2C(=O)[C@H]2CCCN2C(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(O)=O)NC(=O)CNC(=O)[C@H](CCCNC(N)=N)NC1=O |r| Show InChI InChI=1S/C37H61N11O10/c1-19(2)15-23-32(54)44-22(9-6-12-40-37(38)39)31(53)41-18-28(49)43-24(17-29(50)51)33(55)46-25(16-20(3)4)35(57)48-14-8-11-27(48)36(58)47-13-7-10-26(47)34(56)42-21(5)30(52)45-23/h19-27H,6-18H2,1-5H3,(H,41,53)(H,42,56)(H,43,49)(H,44,54)(H,45,52)(H,46,55)(H,50,51)(H4,38,39,40)/t21-,22-,23-,24-,25-,26-,27+/m0/s1	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	32	n/a	n/a	n/a	n/a	n/a	n/a
Technische Universit£t M£nchen Curated by ChEMBL					Assay Description Inhibition of LAP binding to human integrin alphavbeta6 receptor after 1 hr by solid-phase binding assay				J Med Chem 62: 2024-2037 (2019) Article DOI: 10.1021/acs.jmedchem.8b01588
					More data for this Ligand-Target Pair