null
SMILES: Cc1nc(C)n(n1)-c1cc(nc(C)n1)C1CC1c1nc2ccccn2c1C
InChI Key: InChIKey=WGHDYOHZXVHSJS-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50530442 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A
(Homo sapiens (Human)) | BDBM50530442
![PNG](/data/jpeg/tenK5053/BindingDB_50530442.png) (CHEMBL4461114)Show SMILES Cc1nc(C)n(n1)-c1cc(nc(C)n1)C1CC1c1nc2ccccn2c1C Show InChI InChI=1S/C20H21N7/c1-11-20(24-18-7-5-6-8-26(11)18)16-9-15(16)17-10-19(23-12(2)22-17)27-14(4)21-13(3)25-27/h5-8,10,15-16H,9H2,1-4H3 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| PC cid PC sid UniChem
| Article PubMed
| 2.10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Palack£ University
Curated by ChEMBL
| Assay Description Inhibition of human PDE10 |
Eur J Med Chem 181: (2019)
Article DOI: 10.1016/j.ejmech.2019.111569 BindingDB Entry DOI: 10.7270/Q2H41VXG |
More data for this Ligand-Target Pair | |
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A
(Homo sapiens (Human)) | BDBM50530442
![PNG](/data/jpeg/tenK5053/BindingDB_50530442.png) (CHEMBL4461114)Show SMILES Cc1nc(C)n(n1)-c1cc(nc(C)n1)C1CC1c1nc2ccccn2c1C Show InChI InChI=1S/C20H21N7/c1-11-20(24-18-7-5-6-8-26(11)18)16-9-15(16)17-10-19(23-12(2)22-17)27-14(4)21-13(3)25-27/h5-8,10,15-16H,9H2,1-4H3 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| PC cid PC sid UniChem
| Article PubMed
| 2.10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Palack£ University
Curated by ChEMBL
| Assay Description Inhibition of human PDE10 |
Eur J Med Chem 181: (2019)
Article DOI: 10.1016/j.ejmech.2019.111569 BindingDB Entry DOI: 10.7270/Q2H41VXG |
More data for this Ligand-Target Pair | |