BDBM50530655 CHEMBL4585479

SMILES: Cc1nc(Nc2nccc(n2)-c2sc(nc2-c2ccc(F)cc2)C2CCNCC2)ccc1F

InChI Key: InChIKey=ZWDIDKUSTKOXBW-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50530655   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cGMP-dependent protein kinase (Plasmodium falciparum)	BDBM50530655 (CHEMBL4585479) Show SMILES Cc1nc(Nc2nccc(n2)-c2sc(nc2-c2ccc(F)cc2)C2CCNCC2)ccc1F Show InChI InChI=1S/C24H22F2N6S/c1-14-18(26)6-7-20(29-14)31-24-28-13-10-19(30-24)22-21(15-2-4-17(25)5-3-15)32-23(33-22)16-8-11-27-12-9-16/h2-7,10,13,16,27H,8-9,11-12H2,1H3,(H,28,29,30,31)	PDB GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of Plasmodium falciparum full length N-terminal His-tagged PKG expressed in Escherichia coli RosettaTM 2(DE3) pLysS cells using FAM-GRTGRR...				J Med Chem 62: 9217-9235 (2019) Article DOI: 10.1021/acs.jmedchem.9b01099
					More data for this Ligand-Target Pair
cGMP-dependent protein kinase (Plasmodium falciparum)	BDBM50530655 (CHEMBL4585479) Show SMILES Cc1nc(Nc2nccc(n2)-c2sc(nc2-c2ccc(F)cc2)C2CCNCC2)ccc1F Show InChI InChI=1S/C24H22F2N6S/c1-14-18(26)6-7-20(29-14)31-24-28-13-10-19(30-24)22-21(15-2-4-17(25)5-3-15)32-23(33-22)16-8-11-27-12-9-16/h2-7,10,13,16,27H,8-9,11-12H2,1H3,(H,28,29,30,31)	PDB GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of Plasmodium falciparum full length N-terminal His-tagged PKG expressed in Escherichia coli RosettaTM 2(DE3) pLysS cells using FAM-GRTGRR...				J Med Chem 62: 9217-9235 (2019) Article DOI: 10.1021/acs.jmedchem.9b01099
					More data for this Ligand-Target Pair