BDBM50531773 CHEMBL4475740

SMILES: OC(=O)c1cc2cc(\C=C\c3cccc(c3)[N+]([O-])=O)ccc2cc1O

InChI Key: InChIKey=QPSULSJAUWKSBP-SNAWJCMRSA-N

Data: 4 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50531773   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glutamate [NMDA] receptor subunit epsilon 1/zeta 1 (Rattus norvegicus (Rat)-RAT)	BDBM50531773 (CHEMBL4475740) Show SMILES OC(=O)c1cc2cc(\C=C\c3cccc(c3)[N+]([O-])=O)ccc2cc1O Show InChI InChI=1S/C19H13NO5/c21-18-11-14-7-6-13(8-15(14)10-17(18)19(22)23)5-4-12-2-1-3-16(9-12)20(24)25/h1-11,21H,(H,22,23)/b5-4+	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	9.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Bristol Curated by ChEMBL					Assay Description Negative allosteric modulation of rat GluN1/GluN2A expressed in Xenopus laevis oocytes assessed as inhibition of L-glutamate/glycine-induced current ...				Eur J Med Chem 164: 471-498 (2019) Article DOI: 10.1016/j.ejmech.2018.12.054
					More data for this Ligand-Target Pair
Ionotropic glutamate receptor NMDA 1/2D (RAT-Rattus norvegicus (Rat))	BDBM50531773 (CHEMBL4475740) Show SMILES OC(=O)c1cc2cc(\C=C\c3cccc(c3)[N+]([O-])=O)ccc2cc1O Show InChI InChI=1S/C19H13NO5/c21-18-11-14-7-6-13(8-15(14)10-17(18)19(22)23)5-4-12-2-1-3-16(9-12)20(24)25/h1-11,21H,(H,22,23)/b5-4+	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Bristol Curated by ChEMBL					Assay Description Negative allosteric modulation of rat GluN1/GluN2D expressed in Xenopus laevis oocytes assessed as inhibition of L-glutamate/glycine-induced current ...				Eur J Med Chem 164: 471-498 (2019) Article DOI: 10.1016/j.ejmech.2018.12.054
					More data for this Ligand-Target Pair
Glutamate [NMDA] receptor subunit epsilon 2/zeta 1 (Rattus norvegicus (Rat)-RAT)	BDBM50531773 (CHEMBL4475740) Show SMILES OC(=O)c1cc2cc(\C=C\c3cccc(c3)[N+]([O-])=O)ccc2cc1O Show InChI InChI=1S/C19H13NO5/c21-18-11-14-7-6-13(8-15(14)10-17(18)19(22)23)5-4-12-2-1-3-16(9-12)20(24)25/h1-11,21H,(H,22,23)/b5-4+	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	9.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Bristol Curated by ChEMBL					Assay Description Negative allosteric modulation of rat GluN1/GluN2B expressed in Xenopus laevis oocytes assessed as inhibition of L-glutamate/glycine-induced current ...				Eur J Med Chem 164: 471-498 (2019) Article DOI: 10.1016/j.ejmech.2018.12.054
					More data for this Ligand-Target Pair
Glutamate [NMDA] receptor subunit epsilon 3/zeta 1 (RAT-Rattus norvegicus (Rat))	BDBM50531773 (CHEMBL4475740) Show SMILES OC(=O)c1cc2cc(\C=C\c3cccc(c3)[N+]([O-])=O)ccc2cc1O Show InChI InChI=1S/C19H13NO5/c21-18-11-14-7-6-13(8-15(14)10-17(18)19(22)23)5-4-12-2-1-3-16(9-12)20(24)25/h1-11,21H,(H,22,23)/b5-4+	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	7.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Bristol Curated by ChEMBL					Assay Description Negative allosteric modulation of rat GluN1/GluN2C expressed in Xenopus laevis oocytes assessed as inhibition of L-glutamate/glycine-induced current ...				Eur J Med Chem 164: 471-498 (2019) Article DOI: 10.1016/j.ejmech.2018.12.054
					More data for this Ligand-Target Pair