BDBM50534516 CHEMBL4545901

SMILES: ONC(=O)CC(O)c1ccc(Cl)cc1Cl

InChI Key: InChIKey=ICXJMRZQQYLVJY-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50534516   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Urease subunit beta (Helicobacter pylori (strain ATCC 700392 / 26695) (...)	BDBM50534516 (CHEMBL4545901) Show SMILES ONC(=O)CC(O)c1ccc(Cl)cc1Cl Show InChI InChI=1S/C9H9Cl2NO3/c10-5-1-2-6(7(11)3-5)8(13)4-9(14)12-15/h1-3,8,13,15H,4H2,(H,12,14)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.34E+4	n/a	n/a	n/a	n/a	n/a	n/a
Jishou University Curated by ChEMBL					Assay Description Inhibition of Helicobacter pylori urease using urea as substrate assessed as ammonia production after 50 mins by indophenol method				Bioorg Med Chem 24: 4519-4527 (2016) Article DOI: 10.1016/j.bmc.2016.07.052
					More data for this Ligand-Target Pair