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SMILES: Fc1ccc(c(F)n1)-c1ccc(CNS(=O)(=O)c2cc3cc(Cl)ccc3[nH]2)cc1

InChI Key: InChIKey=DVRQCCQUAREQRP-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50534860   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Cannabinoid receptor 1


(Homo sapiens (Human))		BDBM50534860
PNG
(CHEMBL4449492)
Show SMILES Fc1ccc(c(F)n1)-c1ccc(CNS(=O)(=O)c2cc3cc(Cl)ccc3[nH]2)cc1
Show InChI InChI=1S/C20H14ClF2N3O2S/c21-15-5-7-17-14(9-15)10-19(25-17)29(27,28)24-11-12-1-3-13(4-2-12)16-6-8-18(22)26-20(16)23/h1-10,24-25H,11H2
PDB

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PC cid
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Article
PubMed
n/an/a 4n/an/an/an/an/an/a



University of Aberdeen

Curated by ChEMBL


Assay Description
Negative allosteric modulation of human CB1 receptor expressed in CHO-K1 cells assessed as inhibition of CP55940 induced beta arrestin recruitment pr...

Bioorg Med Chem Lett 26: 4403-4407 (2016)


Article DOI: 10.1016/j.bmcl.2016.08.018
BindingDB Entry DOI: 10.7270/Q2P84GD8
More data for this
Ligand-Target Pair