BDBM50535262 CHEMBL4474542

SMILES: Brc1ccc(Cn2c(Cn3ccnc3)nc3ccccc23)cc1

InChI Key: InChIKey=JPWVWOAGUCXZLR-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50535262   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Heme oxygenase 2 (Rattus norvegicus (rat))	BDBM50535262 (CHEMBL4474542) Show SMILES Brc1ccc(Cn2c(Cn3ccnc3)nc3ccccc23)cc1 Show InChI InChI=1S/C18H15BrN4/c19-15-7-5-14(6-8-15)11-23-17-4-2-1-3-16(17)21-18(23)12-22-10-9-20-13-22/h1-10,13H,11-12H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Catania Curated by ChEMBL					Assay Description Inhibition of HO-2 in Sprague-Dawley rat brain microsomes using NADPH as substrate preincubated for 10 mins followed by substrate addition and measur...				Eur J Med Chem 167: 439-453 (2019) Article DOI: 10.1016/j.ejmech.2019.02.027
					More data for this Ligand-Target Pair
Heme oxygenase 1 (Rattus norvegicus (rat))	BDBM50535262 (CHEMBL4474542) Show SMILES Brc1ccc(Cn2c(Cn3ccnc3)nc3ccccc23)cc1 Show InChI InChI=1S/C18H15BrN4/c19-15-7-5-14(6-8-15)11-23-17-4-2-1-3-16(17)21-18(23)12-22-10-9-20-13-22/h1-10,13H,11-12H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Catania Curated by ChEMBL					Assay Description Inhibition of HO-1 in Sprague-Dawley rat spleen microsomes using NADPH as substrate preincubated for 10 mins followed by substrate addition and measu...				Eur J Med Chem 167: 439-453 (2019) Article DOI: 10.1016/j.ejmech.2019.02.027
					More data for this Ligand-Target Pair