BDBM50535324 CHEMBL4443510

SMILES: O=C(CCSC(=S)N1CCCCC1)Nc1cccc(NC(=O)c2ccccn2)c1

InChI Key: InChIKey=IVMJQHQQWWOXKP-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50535324   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50535324 (CHEMBL4443510) Show SMILES O=C(CCSC(=S)N1CCCCC1)Nc1cccc(NC(=O)c2ccccn2)c1 Show InChI InChI=1S/C21H24N4O2S2/c26-19(10-14-29-21(28)25-12-4-1-5-13-25)23-16-7-6-8-17(15-16)24-20(27)18-9-2-3-11-22-18/h2-3,6-9,11,15H,1,4-5,10,12-14H2,(H,23,26)(H,24,27)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	113	n/a	n/a	n/a	n/a	n/a	n/a
Mansoura University Curated by ChEMBL					Assay Description Inhibition of human VEGFR2 in human A549 cells incubated for over night by ELISA method				Eur J Med Chem 168: 315-329 (2019) Article DOI: 10.1016/j.ejmech.2019.02.050
					More data for this Ligand-Target Pair