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BDBM50537561 CHEMBL388502

SMILES: CN(C)CCCn1c(N)nc2ccc3OC(CN(C)C)Cc3c12

InChI Key: InChIKey=PFHMRNGLRJXGSW-UHFFFAOYSA-N

Data: 1 Kd

PDB links: 1 PDB ID matches this monomer.

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50537561   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Hepatitis C virus NS5B RNA-dependent RNA polymerase


(Hepatitis C virus)		BDBM50537561
PNG
(CHEMBL388502)
Show SMILES CN(C)CCCn1c(N)nc2ccc3OC(CN(C)C)Cc3c12
Show InChI InChI=1S/C17H27N5O/c1-20(2)8-5-9-22-16-13-10-12(11-21(3)4)23-15(13)7-6-14(16)19-17(22)18/h6-7,12H,5,8-11H2,1-4H3,(H2,18,19)
UniProtKB/TrEMBL

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
PDB
UniChem
Article
PubMed
n/an/an/a 1.70E+3n/an/an/an/an/a



Institute of Pharmaceutical Education and Research

Curated by ChEMBL


Assay Description
Inhibitory potency against isolated epidermal growth factor receptor (EGFR) from human A431 carcinoma cells

Eur J Med Chem 164: 576-601 (2019)


Article DOI: 10.1007/s00044-005-0131-1
BindingDB Entry DOI: 10.7270/Q2RR224D
More data for this
Ligand-Target Pair