BDBM50542108 CHEMBL4641174

SMILES: C1C[C@@H](CN1)Oc1ccc2cncc(-c3ccc4ccccc4c3)c2c1

InChI Key: InChIKey=AUPQHKSJXRTZNA-NRFANRHFSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50542108   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Protein kinase C iota type/zeta type (Homo sapiens (Human))	BDBM50542108 (CHEMBL4641174) Show SMILES C1C[C@@H](CN1)Oc1ccc2cncc(-c3ccc4ccccc4c3)c2c1 |r| Show InChI InChI=1S/C23H20N2O/c1-2-4-17-11-18(6-5-16(17)3-1)23-15-25-13-19-7-8-20(12-22(19)23)26-21-9-10-24-14-21/h1-8,11-13,15,21,24H,9-10,14H2/t21-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	PubMed	n/a	n/a	356	n/a	n/a	n/a	n/a	n/a	n/a
Asahi Kasei Pharma Corporation Curated by ChEMBL					Assay Description Inhibition of recombinant human PKCzeta using biotin-KKKKRFSFKKSFK substrate and ATP incubated for 30 mins by TR-FRET method				J Med Chem 63: 7143-7162 (2020)
					More data for this Ligand-Target Pair