BDBM50543171 CHEMBL4645573
SMILES: Cc1cc(C(O)=O)c(C)[nH]1
InChI Key: InChIKey=VDVWTJFVFQVCFN-UHFFFAOYSA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Palmitoleoyl-protein carboxylesterase NOTUM (Homo sapiens (Human)) | BDBM50543171 (CHEMBL4645573) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem | PubMed | n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
University College London Curated by ChEMBL | Assay Description Inhibition of human Notum (S81 to T451 residues) Cys330Ser mutant expressed in HEK293S GnTI cells using OPTS as substrate incubated for 40 mins by fl... | J Med Chem 63: 9464-9483 (2020) | |||||||||||
More data for this Ligand-Target Pair |