BDBM50544704 CHEMBL4633098

SMILES: Clc1ccc(CNC(=O)[C@@H]2CCC(=O)N2Cc2ccccc2Cl)c(Cl)c1

InChI Key: InChIKey=IBDMEASLCIGVQS-KRWDZBQOSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50544704   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
P2X purinoceptor 7 (Homo sapiens (Human))	BDBM50544704 (CHEMBL4633098) Show SMILES Clc1ccc(CNC(=O)[C@@H]2CCC(=O)N2Cc2ccccc2Cl)c(Cl)c1 |r| Show InChI InChI=1S/C19H17Cl3N2O2/c20-14-6-5-12(16(22)9-14)10-23-19(26)17-7-8-18(25)24(17)11-13-3-1-2-4-15(13)21/h1-6,9,17H,7-8,10-11H2,(H,23,26)/t17-/m0/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	PubMed	n/a	n/a	3.46E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ de Lille Curated by ChEMBL					Assay Description Inhibition of human P2X7 expressed in human HEK293 cells assessed as reduction in BzATP-stimulated TO-PRO-3 incorporation preincubated with compound ...				J Med Chem 63: 2074-2094 (2020)
					More data for this Ligand-Target Pair