null
SMILES: Cc1noc(C)c1-c1ccc2nc(nc(N3CCOC[C@@H]3C3CCC3)c2c1)-c1cnn(CC(C)(C)O)c1
InChI Key:
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Bromodomain-containing protein 4 (Homo sapiens (Human)) | BDBM50545920 (CHEMBL4759032) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | 195 | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Competitive binding affinity to human partial length BRD4 (BD1,2) (N44 to E460 residues) expressed in bacterial expression system by BROMOscan assay | Citation and Details Article DOI: 10.1016/j.bmcl.2019.03.014 BindingDB Entry DOI: 10.7270/Q2FT8QMQ | |||||||||||
More data for this Ligand-Target Pair |