null
SMILES: Cl.Cl.COC(=O)N[C@@H](C(C)C)C(=O)N1CCC[C@H]1c1ncc([nH]1)C#CC#Cc1c(C)cc(cc1-c1ccccc1)-c1cnc([nH]1)[C@@H]1CCCN1C(=O)[C@@H](NC(=O)OC)C(C)C
InChI Key:
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Nonstructural protein 5A (Hepatitis C virus) | BDBM50547635 (CHEMBL4798433) | PDB UniProtKB/TrEMBL GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 0.0270 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of HCV genotype 5a NS5A infected in Huh7 cells assessed as reduction in viral replication incubated 3 days and measured by bright Glo-luci... | Citation and Details Article DOI: 10.1016/j.bmc.2020.115716 BindingDB Entry DOI: 10.7270/Q29K4FTX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Nonstructural protein 5A (Hepatitis C virus) | BDBM50547635 (CHEMBL4798433) | PDB UniProtKB/TrEMBL GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 0.364 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of HCV genotype 3a NS5A infected in Huh7 cells assessed as reduction in viral replication incubated 3 days and measured by bright Glo-luci... | Citation and Details Article DOI: 10.1016/j.bmc.2020.115716 BindingDB Entry DOI: 10.7270/Q29K4FTX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Nonstructural protein 5A (Hepatitis C virus) | BDBM50547635 (CHEMBL4798433) | PDB UniProtKB/TrEMBL GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 0.00800 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of HCV genotype 2a NS5A infected in Huh7 cells assessed as reduction in viral replication incubated 3 days and measured by bright Glo-luci... | Citation and Details Article DOI: 10.1016/j.bmc.2020.115716 BindingDB Entry DOI: 10.7270/Q29K4FTX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Nonstructural protein 5A (Hepatitis C virus) | BDBM50547635 (CHEMBL4798433) | PDB UniProtKB/TrEMBL GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 0.0370 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of HCV genotype 1a NS5A infected in Huh7 cells assessed as reduction in viral replication incubated 3 days and measured by bright Glo-luci... | Citation and Details Article DOI: 10.1016/j.bmc.2020.115716 BindingDB Entry DOI: 10.7270/Q29K4FTX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Nonstructural protein 5A (Hepatitis C virus) | BDBM50547635 (CHEMBL4798433) | PDB UniProtKB/TrEMBL GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 0.00200 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of HCV genotype 1b NS5A infected in Huh7 cells assessed as reduction in viral replication incubated 3 days and measured by Celltiter Glo a... | Citation and Details Article DOI: 10.1016/j.bmc.2020.115716 BindingDB Entry DOI: 10.7270/Q29K4FTX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Nonstructural protein 5A (Hepatitis C virus) | BDBM50547635 (CHEMBL4798433) | PDB UniProtKB/TrEMBL GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 0.00600 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of HCV genotype 4a NS5A infected in Huh7 cells assessed as reduction in viral replication incubated 3 days and measured by bright Glo-luci... | Citation and Details Article DOI: 10.1016/j.bmc.2020.115716 BindingDB Entry DOI: 10.7270/Q29K4FTX | |||||||||||
More data for this Ligand-Target Pair |