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SMILES: CC(C)(Oc1ccc(cn1)-c1cnc(N)c(c1)-c1ccc(Cl)cc1)C(O)=O

InChI Key:

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50550629   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase kinase kinase kinase 4 (Homo sapiens (Human))	BDBM50550629 (CHEMBL4750540) Show SMILES CC(C)(Oc1ccc(cn1)-c1cnc(N)c(c1)-c1ccc(Cl)cc1)C(O)=O Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	197	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of MAP4K4 in human GripTite 293 MSR cells assessed as reduction in TRAF2 Ser/Thr phosphorylation incubated for 1.5 hrs by ELISA				Citation and Details Article DOI: 10.1021/acs.jmedchem.8b00152 BindingDB Entry DOI: 10.7270/Q2TH8RBV
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase kinase kinase kinase 4 (Homo sapiens (Human))	BDBM50550629 (CHEMBL4750540) Show SMILES CC(C)(Oc1ccc(cn1)-c1cnc(N)c(c1)-c1ccc(Cl)cc1)C(O)=O Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.30	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of recombinant human GST-tagged MAP4K4 catalytic domain (1 to 328 residues) expressed in baculovirus expression system pre-incubated for 3...				Citation and Details Article DOI: 10.1021/acs.jmedchem.8b00152 BindingDB Entry DOI: 10.7270/Q2TH8RBV
					More data for this Ligand-Target Pair