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SMILES: OC=O.CNCCNc1c(C(=O)Nc2ccc(cc2)C(O)=O)c(=O)[nH]c2c(NC)cc(F)cc12

InChI Key:

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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50554218   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
DNA gyrase subunit A/B


(Escherichia coli (strain K12))		BDBM50554218
PNG
(CHEMBL4779138)
Show SMILES OC=O.CNCCNc1c(C(=O)Nc2ccc(cc2)C(O)=O)c(=O)[nH]c2c(NC)cc(F)cc12
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 2.10n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of Escherichia coli DNA gyrase by measuring supercoiling activity incubated for 60 mins by fluorescence based assay

Citation and Details

Article DOI: 10.1016/j.bmc.2020.115776
BindingDB Entry DOI: 10.7270/Q2W66QFJ
More data for this
Ligand-Target Pair