BindingDB logo
myBDB logout

null

SMILES: CC(O)(C(=O)Nc1ccc2N(c3ccncc3)C(=O)c3cccnc3Oc2c1)C(F)(F)F

InChI Key:

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50565114   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Cyclin-dependent kinase 8


(Homo sapiens (Human))		BDBM50565114
PNG
(CHEMBL4786883)
Show SMILES CC(O)(C(=O)Nc1ccc2N(c3ccncc3)C(=O)c3cccnc3Oc2c1)C(F)(F)F
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a>1.00E+4n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of CDK8 (unknown origin)

Citation and Details

Article DOI: 10.1016/j.ejmech.2020.112443
BindingDB Entry DOI: 10.7270/Q2TF023Q
More data for this
Ligand-Target Pair