null

SMILES: CNC(=O)c1cc(cc(n1)C(CC#N)c1ccccc1)C(=O)N[C@H]1C[C@@H]1C

InChI Key:

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50566695   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Bromodomain-containing protein 4 (Homo sapiens (Human))	BDBM50566695 (CHEMBL4846439) Show SMILES CNC(=O)c1cc(cc(n1)C(CC#N)c1ccccc1)C(=O)N[C@H]1C[C@@H]1C |r| Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Displacement of Alexa Fluor 647 labelled ligand from 6His-Thr tagged BRD4 BD2/BD1 Y97A mutant (1 to 477 residue) (unknown origin) measured after 30 m...				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c02155 BindingDB Entry DOI: 10.7270/Q2JH3QXP
					More data for this Ligand-Target Pair
Bromodomain-containing protein 4 (Homo sapiens (Human))	BDBM50566695 (CHEMBL4846439) Show SMILES CNC(=O)c1cc(cc(n1)C(CC#N)c1ccccc1)C(=O)N[C@H]1C[C@@H]1C |r| Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.51E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Displacement of Alexa Fluor 647 labelled ligand from 6His-Thr tagged BRD4 BD1/BD2 Y390A mutant (1 to 477 residue) (unknown origin) measured after 30 ...				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c02155 BindingDB Entry DOI: 10.7270/Q2JH3QXP
					More data for this Ligand-Target Pair