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SMILES: CCc1cc(Nc2nc(N[C@@H](C)c3ccc(cn3)C#N)nc3cccc(F)c23)n[nH]1

InChI Key:

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50566941   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Aurora kinase A (Homo sapiens (Human))	BDBM50566941 (CHEMBL4849245) Show SMILES CCc1cc(Nc2nc(N[C@@H](C)c3ccc(cn3)C#N)nc3cccc(F)c23)n[nH]1 |r| Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	220	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of recombinant full length human Aurora A using LRRASLG as substrate incubated for 40 mins in presence of [gamma-33ATP] by radiometric sci...				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00506 BindingDB Entry DOI: 10.7270/Q20K2D97
					More data for this Ligand-Target Pair
G protein-coupled receptor kinase 6 (Homo sapiens (Human))	BDBM50566941 (CHEMBL4849245) Show SMILES CCc1cc(Nc2nc(N[C@@H](C)c3ccc(cn3)C#N)nc3cccc(F)c23)n[nH]1 |r| Show InChI	PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	91	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of recombinant full-length human GRK6 using casein as substrate measured after 80 mins in presence of [gamma33P]ATP by radiometric scintil...				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00506 BindingDB Entry DOI: 10.7270/Q20K2D97
					More data for this Ligand-Target Pair