null

SMILES: CCCCc1nc(=O)c(c(O)n1-c1c(OC)cccc1OC)S(=O)(=O)c1ccc(cc1)-c1cccnc1

InChI Key:

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50567160   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Apelin receptor (Homo sapiens (Human))	BDBM50567160 (CHEMBL4873216) Show SMILES CCCCc1nc(=O)c(c(O)n1-c1c(OC)cccc1OC)S(=O)(=O)c1ccc(cc1)-c1cccnc1 |(55.23,-6.18,;56.56,-6.95,;57.89,-6.19,;59.23,-6.95,;60.56,-6.19,;60.56,-4.64,;61.89,-3.87,;61.89,-2.33,;63.23,-4.64,;63.23,-6.19,;64.57,-6.95,;61.89,-6.96,;61.9,-8.49,;63.23,-9.26,;64.56,-8.49,;65.89,-9.25,;63.23,-10.8,;61.89,-11.57,;60.56,-10.8,;60.56,-9.26,;59.23,-8.49,;57.89,-9.26,;64.55,-3.86,;63.78,-2.52,;65.32,-2.52,;65.89,-4.63,;65.89,-6.16,;67.23,-6.93,;68.56,-6.15,;68.55,-4.6,;67.21,-3.85,;69.9,-6.91,;71.22,-6.14,;72.56,-6.89,;72.57,-8.44,;71.24,-9.22,;69.9,-8.46,)| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	0.0400	n/a	n/a	n/a	n/a
TBA					Assay Description Agonist activity at human APJ receptor assessed as effect on cAMP accumulation by cAMP-Glo assay				Citation and Details Article DOI: 10.1016/j.bmcl.2021.128325 BindingDB Entry DOI: 10.7270/Q2KD22N4
					More data for this Ligand-Target Pair
Apelin receptor (Mus musculus)	BDBM50567160 (CHEMBL4873216) Show SMILES CCCCc1nc(=O)c(c(O)n1-c1c(OC)cccc1OC)S(=O)(=O)c1ccc(cc1)-c1cccnc1 |(55.23,-6.18,;56.56,-6.95,;57.89,-6.19,;59.23,-6.95,;60.56,-6.19,;60.56,-4.64,;61.89,-3.87,;61.89,-2.33,;63.23,-4.64,;63.23,-6.19,;64.57,-6.95,;61.89,-6.96,;61.9,-8.49,;63.23,-9.26,;64.56,-8.49,;65.89,-9.25,;63.23,-10.8,;61.89,-11.57,;60.56,-10.8,;60.56,-9.26,;59.23,-8.49,;57.89,-9.26,;64.55,-3.86,;63.78,-2.52,;65.32,-2.52,;65.89,-4.63,;65.89,-6.16,;67.23,-6.93,;68.56,-6.15,;68.55,-4.6,;67.21,-3.85,;69.9,-6.91,;71.22,-6.14,;72.56,-6.89,;72.57,-8.44,;71.24,-9.22,;69.9,-8.46,)| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	0.0500	n/a	n/a	n/a	n/a
TBA					Assay Description Agonist activity at mouse APJ receptor assessed as effect on cAMP accumulation by cAMP-Glo assay				Citation and Details Article DOI: 10.1016/j.bmcl.2021.128325 BindingDB Entry DOI: 10.7270/Q2KD22N4
					More data for this Ligand-Target Pair
Apelin receptor (Rattus norvegicus)	BDBM50567160 (CHEMBL4873216) Show SMILES CCCCc1nc(=O)c(c(O)n1-c1c(OC)cccc1OC)S(=O)(=O)c1ccc(cc1)-c1cccnc1 |(55.23,-6.18,;56.56,-6.95,;57.89,-6.19,;59.23,-6.95,;60.56,-6.19,;60.56,-4.64,;61.89,-3.87,;61.89,-2.33,;63.23,-4.64,;63.23,-6.19,;64.57,-6.95,;61.89,-6.96,;61.9,-8.49,;63.23,-9.26,;64.56,-8.49,;65.89,-9.25,;63.23,-10.8,;61.89,-11.57,;60.56,-10.8,;60.56,-9.26,;59.23,-8.49,;57.89,-9.26,;64.55,-3.86,;63.78,-2.52,;65.32,-2.52,;65.89,-4.63,;65.89,-6.16,;67.23,-6.93,;68.56,-6.15,;68.55,-4.6,;67.21,-3.85,;69.9,-6.91,;71.22,-6.14,;72.56,-6.89,;72.57,-8.44,;71.24,-9.22,;69.9,-8.46,)| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	0.0500	n/a	n/a	n/a	n/a
TBA					Assay Description Agonist activity at rat APJ receptor assessed as effect on cAMP accumulation by cAMP-Glo assay				Citation and Details Article DOI: 10.1016/j.bmcl.2021.128325 BindingDB Entry DOI: 10.7270/Q2KD22N4
					More data for this Ligand-Target Pair