null
SMILES: CN1CCC(=CC1)C1=Nc2cc(C)ccc2Nc2ccc(C)cc12
InChI Key:
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
D(1A) dopamine receptor (Homo sapiens (Human)) | BDBM50569112![]() (CHEMBL4865663) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | 57 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Antagonist activity at human D1 receptor expressed in CHO cells assessed as inhibition of dopamine-induced calcium accumulation | Citation and Details Article DOI: 10.1016/j.bmcl.2021.127911 BindingDB Entry DOI: 10.7270/Q2C82F2T | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(2) dopamine receptor (Homo sapiens (Human)) | BDBM50569112![]() (CHEMBL4865663) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | 694 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Antagonist activity at human D2 receptor expressed in CHO cells assessed as inhibition of dopamine-induced calcium accumulation | Citation and Details Article DOI: 10.1016/j.bmcl.2021.127911 BindingDB Entry DOI: 10.7270/Q2C82F2T | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Muscarinic acetylcholine receptor M4 (Homo sapiens (Human)) | BDBM50569112![]() (CHEMBL4865663) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a |
TBA | Assay Description Agonist activity at muscarinic M4 receptor (unknown origin) expressed in CHO cells | Citation and Details Article DOI: 10.1016/j.bmcl.2021.127911 BindingDB Entry DOI: 10.7270/Q2C82F2T | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Muscarinic acetylcholine receptor M1 (Homo sapiens (Human)) | BDBM50569112![]() (CHEMBL4865663) | UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a |
TBA | Assay Description Agonist activity at muscarinic M1 receptor (unknown origin) expressed in CHO cells | Citation and Details Article DOI: 10.1016/j.bmcl.2021.127911 BindingDB Entry DOI: 10.7270/Q2C82F2T | |||||||||||
More data for this Ligand-Target Pair |