null
SMILES: COc1ccccc1N1CCN(CC1)c1ccccc1NS(=O)(=O)c1ccccc1
InChI Key:
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Mucolipin-1 (Homo sapiens) | BDBM50569856![]() (CHEMBL4875551) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.80E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of human TRPML1deltaNC-YFP expressed in HEK293 cells preincubated for 10 mins followed by stimulation with ML-SA1 and measured after 10 mi... | Citation and Details Article DOI: 10.1016/j.ejmech.2020.112966 BindingDB Entry DOI: 10.7270/Q2862M7H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mucolipin-2 (Homo sapiens) | BDBM50569856![]() (CHEMBL4875551) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | n/a | 1.10E+3 | n/a | n/a | n/a | n/a |
TBA | Assay Description Activation of human TRPML2-YFP expressed in HEK293 cells incubated for 10 mins by Fluo-4 dye calcium imaging based FLIPR analysis | Citation and Details Article DOI: 10.1016/j.ejmech.2020.112966 BindingDB Entry DOI: 10.7270/Q2862M7H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mucolipin-3 (Homo sapiens (Human)) | BDBM50569856![]() (CHEMBL4875551) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 2.17E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of human TRPML3-YFP expressed in HEK293 cells preincubated for 10 mins followed by stimulation with ML-SA1 and measured after 10 mins by F... | Citation and Details Article DOI: 10.1016/j.ejmech.2020.112966 BindingDB Entry DOI: 10.7270/Q2862M7H | |||||||||||
More data for this Ligand-Target Pair |