null
SMILES: [H][C@]12C[C@@]3([H])C4=CCO[C@@]5([H])CC(=O)N6c7ccc(NC(=O)CCCCCCC(=O)Nc8ccc9N%10C(=O)C[C@]%11([H])OCC=C%12CN%13CC[C@@]%14(c9c8)[C@]%13([H])C[C@]%12([H])[C@]%11([H])[C@]%10%14[H])cc7[C@@]1(CCN2C4)[C@]6([H])[C@@]35[H]
InChI Key:
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Glycine receptor subunit alpha-1 (Homo sapiens (Human)) | BDBM50570337 (CHEMBL4860026) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 6.90E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Antagonist activity at human glycine receptor subunit alpha-1 expressed in human tsA201 cells assessed as reduction in glycine-induced response incub... | Citation and Details Article DOI: 10.1021/acs.jnatprod.0c01030 BindingDB Entry DOI: 10.7270/Q2HH6PV6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glycine receptor subunit alpha-1 (Homo sapiens (Human)) | BDBM50570337 (CHEMBL4860026) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 6.92E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Antagonist activity at human glycine receptor subunit alpha-1 expressed in human tsA201 cells assessed as reduction in glycine-induced response incub... | Citation and Details Article DOI: 10.1021/acs.jnatprod.0c01030 BindingDB Entry DOI: 10.7270/Q2HH6PV6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glycine receptor subunit alpha-1/beta (Homo sapiens (Human)) | BDBM50570337 (CHEMBL4860026) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Antagonist activity at human glycine receptor subunit alpha-1beta expressed in HEK293 cells assessed as reduction in glycine-induced currents by whol... | Citation and Details Article DOI: 10.1021/acs.jnatprod.0c01030 BindingDB Entry DOI: 10.7270/Q2HH6PV6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glycine receptor subunit alpha-1/beta (Homo sapiens (Human)) | BDBM50570337 (CHEMBL4860026) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Antagonist activity at human glycine receptor subunit alpha-1beta expressed in human tsA201 cells assessed as reduction in glycine-induced response i... | Citation and Details Article DOI: 10.1021/acs.jnatprod.0c01030 BindingDB Entry DOI: 10.7270/Q2HH6PV6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glycine receptor subunit alpha-1 (Homo sapiens (Human)) | BDBM50570337 (CHEMBL4860026) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Antagonist activity at human glycine receptor subunit alpha-1 expressed in HEK293 cells assessed as reduction in glycine-induced currents by whole-ce... | Citation and Details Article DOI: 10.1021/acs.jnatprod.0c01030 BindingDB Entry DOI: 10.7270/Q2HH6PV6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glycine receptor subunit alpha-1/beta (Homo sapiens (Human)) | BDBM50570337 (CHEMBL4860026) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Antagonist activity at human glycine receptor subunit alpha-1beta expressed in human tsA201 cells assessed as reduction in glycine-induced response i... | Citation and Details Article DOI: 10.1021/acs.jnatprod.0c01030 BindingDB Entry DOI: 10.7270/Q2HH6PV6 | |||||||||||
More data for this Ligand-Target Pair |