null

SMILES: [H][C@]12C[C@@]3([H])C4=CCO[C@@]5([H])CC(=O)N6c7ccc(NC(=O)CCCCNC(=O)CCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOC)cc7[C@@]1(CCN2C4)[C@]6([H])[C@@]35[H]

InChI Key:

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50570355   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glycine receptor subunit alpha-1 (Homo sapiens (Human))	BDBM50570355 (CHEMBL4873527) Show SMILES [H][C@]12C[C@@]3([H])C4=CCO[C@@]5([H])CC(=O)N6c7ccc(NC(=O)CCCCNC(=O)CCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOC)cc7[C@@]1(CCN2C4)[C@]6([H])[C@@]35[H] |r,c:5| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	436	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Displacement of [3H]strychnine from human glycine receptor subunit alpha-1 expressed in HEK293 cell membranes preincubated for 30 mins followed by [3...				Citation and Details Article DOI: 10.1021/acs.jnatprod.0c01030 BindingDB Entry DOI: 10.7270/Q2HH6PV6
					More data for this Ligand-Target Pair
Glycine receptor subunit alpha-1 (Homo sapiens (Human))	BDBM50570355 (CHEMBL4873527) Show SMILES [H][C@]12C[C@@]3([H])C4=CCO[C@@]5([H])CC(=O)N6c7ccc(NC(=O)CCCCNC(=O)CCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOC)cc7[C@@]1(CCN2C4)[C@]6([H])[C@@]35[H] |r,c:5| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.58E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Antagonist activity at human glycine receptor subunit alpha-1 expressed in human tsA201 cells assessed as reduction in glycine-induced response incub...				Citation and Details Article DOI: 10.1021/acs.jnatprod.0c01030 BindingDB Entry DOI: 10.7270/Q2HH6PV6
					More data for this Ligand-Target Pair
Glycine receptor subunit alpha-1/beta (Homo sapiens (Human))	BDBM50570355 (CHEMBL4873527) Show SMILES [H][C@]12C[C@@]3([H])C4=CCO[C@@]5([H])CC(=O)N6c7ccc(NC(=O)CCCCNC(=O)CCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOC)cc7[C@@]1(CCN2C4)[C@]6([H])[C@@]35[H] |r,c:5| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Antagonist activity at human glycine receptor subunit alpha-1beta expressed in human tsA201 cells assessed as reduction in glycine-induced response i...				Citation and Details Article DOI: 10.1021/acs.jnatprod.0c01030 BindingDB Entry DOI: 10.7270/Q2HH6PV6
					More data for this Ligand-Target Pair
Glycine receptor subunit alpha-1 (Homo sapiens (Human))	BDBM50570355 (CHEMBL4873527) Show SMILES [H][C@]12C[C@@]3([H])C4=CCO[C@@]5([H])CC(=O)N6c7ccc(NC(=O)CCCCNC(=O)CCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOC)cc7[C@@]1(CCN2C4)[C@]6([H])[C@@]35[H] |r,c:5| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	137	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Antagonist activity at human glycine receptor subunit alpha-1 assessed as inhibition of glycine-induced current measured at the later state of compou...				Citation and Details Article DOI: 10.1021/acs.jnatprod.0c01030 BindingDB Entry DOI: 10.7270/Q2HH6PV6
					More data for this Ligand-Target Pair
Glycine receptor subunit alpha-1 (Homo sapiens (Human))	BDBM50570355 (CHEMBL4873527) Show SMILES [H][C@]12C[C@@]3([H])C4=CCO[C@@]5([H])CC(=O)N6c7ccc(NC(=O)CCCCNC(=O)CCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOC)cc7[C@@]1(CCN2C4)[C@]6([H])[C@@]35[H] |r,c:5| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	852	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Antagonist activity at human glycine receptor subunit alpha-1 assessed as inhibition of glycine-induced current measured at the onset of compound app...				Citation and Details Article DOI: 10.1021/acs.jnatprod.0c01030 BindingDB Entry DOI: 10.7270/Q2HH6PV6
					More data for this Ligand-Target Pair
Glycine receptor subunit alpha-1 (Homo sapiens (Human))	BDBM50570355 (CHEMBL4873527) Show SMILES [H][C@]12C[C@@]3([H])C4=CCO[C@@]5([H])CC(=O)N6c7ccc(NC(=O)CCCCNC(=O)CCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOC)cc7[C@@]1(CCN2C4)[C@]6([H])[C@@]35[H] |r,c:5| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Antagonist activity at human glycine receptor subunit alpha-1 expressed in human tsA201 cells assessed as reduction in glycine-induced response incub...				Citation and Details Article DOI: 10.1021/acs.jnatprod.0c01030 BindingDB Entry DOI: 10.7270/Q2HH6PV6
					More data for this Ligand-Target Pair
Glycine receptor subunit alpha-1/beta (Homo sapiens (Human))	BDBM50570355 (CHEMBL4873527) Show SMILES [H][C@]12C[C@@]3([H])C4=CCO[C@@]5([H])CC(=O)N6c7ccc(NC(=O)CCCCNC(=O)CCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOC)cc7[C@@]1(CCN2C4)[C@]6([H])[C@@]35[H] |r,c:5| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Antagonist activity at human glycine receptor subunit alpha-1beta expressed in human tsA201 cells assessed as reduction in glycine-induced response i...				Citation and Details Article DOI: 10.1021/acs.jnatprod.0c01030 BindingDB Entry DOI: 10.7270/Q2HH6PV6
					More data for this Ligand-Target Pair