null

SMILES: Cl.COc1cccc(OC)c1-c1cc(nn1C1CCCC1)C(=O)N[C@@H](CCN1CCOCC1)CC(=O)NC1CCC1

InChI Key:

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50571386   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Apelin receptor (Homo sapiens (Human))	BDBM50571386 (CHEMBL4863277) Show SMILES Cl.COc1cccc(OC)c1-c1cc(nn1C1CCCC1)C(=O)N[C@@H](CCN1CCOCC1)CC(=O)NC1CCC1 |r,wU:24.26,(81.45,-37.46,;71.97,-34.84,;73.11,-35.87,;72.79,-37.37,;71.33,-37.85,;71.01,-39.36,;72.17,-40.39,;73.63,-39.91,;74.77,-40.93,;74.46,-42.44,;73.94,-38.4,;75.39,-37.93,;75.87,-36.46,;77.41,-36.46,;77.89,-37.92,;76.64,-38.83,;76.65,-40.37,;75.41,-41.27,;75.88,-42.74,;77.42,-42.74,;77.9,-41.27,;78.31,-35.21,;77.68,-33.81,;79.84,-35.37,;80.75,-34.12,;80.12,-32.72,;81.02,-31.47,;80.39,-30.06,;81.31,-28.81,;80.68,-27.41,;79.15,-27.25,;78.24,-28.49,;78.87,-29.91,;82.28,-34.28,;83.18,-33.03,;82.55,-31.63,;84.71,-33.19,;85.62,-31.95,;87.13,-31.7,;86.89,-30.18,;85.37,-30.43,)| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	1.35E+3	n/a	n/a	n/a	n/a
TBA					Assay Description Agonist activity at human AGTRL1 expressed in CHO-K1 cells assessed as induction of beta-arrestin 2 recruitment incubated for 90 mins by PathHunter a...				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01448 BindingDB Entry DOI: 10.7270/Q2TH8RGN
					More data for this Ligand-Target Pair
Apelin receptor (Homo sapiens (Human))	BDBM50571386 (CHEMBL4863277) Show SMILES Cl.COc1cccc(OC)c1-c1cc(nn1C1CCCC1)C(=O)N[C@@H](CCN1CCOCC1)CC(=O)NC1CCC1 |r,wU:24.26,(81.45,-37.46,;71.97,-34.84,;73.11,-35.87,;72.79,-37.37,;71.33,-37.85,;71.01,-39.36,;72.17,-40.39,;73.63,-39.91,;74.77,-40.93,;74.46,-42.44,;73.94,-38.4,;75.39,-37.93,;75.87,-36.46,;77.41,-36.46,;77.89,-37.92,;76.64,-38.83,;76.65,-40.37,;75.41,-41.27,;75.88,-42.74,;77.42,-42.74,;77.9,-41.27,;78.31,-35.21,;77.68,-33.81,;79.84,-35.37,;80.75,-34.12,;80.12,-32.72,;81.02,-31.47,;80.39,-30.06,;81.31,-28.81,;80.68,-27.41,;79.15,-27.25,;78.24,-28.49,;78.87,-29.91,;82.28,-34.28,;83.18,-33.03,;82.55,-31.63,;84.71,-33.19,;85.62,-31.95,;87.13,-31.7,;86.89,-30.18,;85.37,-30.43,)| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	237	n/a	n/a	n/a	n/a
TBA					Assay Description Agonist activity at human APJ receptor expressed in CHO cells assessed as inhibition of forskolin-induced cAMP accumulation measured after 40 mins by...				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01448 BindingDB Entry DOI: 10.7270/Q2TH8RGN
					More data for this Ligand-Target Pair