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SMILES: CCOC(=O)n1ccc(Nc2[nH]c3c(c(nn3c(=O)c2-c2ccc(OC)cc2)-c2ccccc2)-c2ccccc2)n1

InChI Key:

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50576016   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
S-adenosylmethionine synthase isoform type-2


(Human)		BDBM50576016
PNG
(CHEMBL4584451)
Show SMILES CCOC(=O)n1ccc(Nc2[nH]c3c(c(nn3c(=O)c2-c2ccc(OC)cc2)-c2ccccc2)-c2ccccc2)n1
PDB

UniProtKB/SwissProt

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PC cid
PC sid
UniChem
Article
PubMed
n/an/a 11n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of recombinant human MAT2A expressed in baculovirus infected Sf9 cells assessed as S-adenosyl methionine production using L-methionine as ...

Citation and Details

Article DOI: 10.1021/acs.jmedchem.0c01895
BindingDB Entry DOI: 10.7270/Q20R9T7P
More data for this
Ligand-Target Pair