null
SMILES: [H][C@@]12C=C(C)CC[C@]1([H])C(C)(C)Oc1cc(CCCCC)cc(O)c21
InChI Key:
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Cannabinoid receptor 2 (Homo sapiens (Human)) | BDBM50577909 (CHEMBL4845760) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 99 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Displacement of [3H]CP55940 from human CB2 receptor transfected in CHO cells measured for 1.5 hrs by liquid scintillation counting analysis | Citation and Details Article DOI: 10.1021/acs.jnatprod.1c00513 BindingDB Entry DOI: 10.7270/Q2251P0M | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cannabinoid receptor 1 (Homo sapiens (Human)) | BDBM50577909 (CHEMBL4845760) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 228 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Displacement of [3H]CP55940 from human CB1 receptor transfected in CHO cells measured for 1.5 hrs by liquid scintillation counting analysis | Citation and Details Article DOI: 10.1021/acs.jnatprod.1c00513 BindingDB Entry DOI: 10.7270/Q2251P0M | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Fatty-acid amide hydrolase 1 (Homo sapiens (Human)) | BDBM50577909 (CHEMBL4845760) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 3.63E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of FAAH (unknown origin) in human U-937 cells using [ethanolamine-1-3H]AEA as substrate preincubated for 30 mins followed by substrate add... | Citation and Details Article DOI: 10.1021/acs.jnatprod.1c00513 BindingDB Entry DOI: 10.7270/Q2251P0M | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Monoglyceride lipase (Homo sapiens (Human)) | BDBM50577909 (CHEMBL4845760) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of MAGL (unknown origin) in human U-937 cells using [ethanolamine-1-3H]AEA as substrate preincubated for 30 mins followed by substrate add... | Citation and Details Article DOI: 10.1021/acs.jnatprod.1c00513 BindingDB Entry DOI: 10.7270/Q2251P0M | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Monoacylglycerol lipase ABHD6 (Homo sapiens (Human)) | BDBM50577909 (CHEMBL4845760) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 3.98E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of human ABHD6 transfected in HEK293 cells using 2-OG as substrate preincubated for 30 mins followed by substrate addition measured after ... | Citation and Details Article DOI: 10.1021/acs.jnatprod.1c00513 BindingDB Entry DOI: 10.7270/Q2251P0M | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Lysophosphatidylserine lipase ABHD12 (Homo sapiens (Human)) | BDBM50577909 (CHEMBL4845760) | KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.41E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of human ABHD12 transfected in HEK293 cells using 2-OG as substrate preincubated for 30 mins followed by substrate addition measured after... | Citation and Details Article DOI: 10.1021/acs.jnatprod.1c00513 BindingDB Entry DOI: 10.7270/Q2251P0M | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cannabinoid receptor 1 (Homo sapiens (Human)) | BDBM50577909 (CHEMBL4845760) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | n/a | 552 | n/a | n/a | n/a | n/a |
TBA | Assay Description Partial agonist activity at human CB1 receptor transfected in CHO cells incubated for 90 mins by scintillation counting based [35S]GTP-gamma-S-bindin... | Citation and Details Article DOI: 10.1021/acs.jnatprod.1c00513 BindingDB Entry DOI: 10.7270/Q2251P0M | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cannabinoid receptor 2 (Homo sapiens (Human)) | BDBM50577909 (CHEMBL4845760) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | n/a | 119 | n/a | n/a | n/a | n/a |
TBA | Assay Description Partial agonist activity at human CB2 receptor transfected in CHO cells incubated for 90 mins by scintillation counting based [35S]GTP-gamma-S-bindin... | Citation and Details Article DOI: 10.1021/acs.jnatprod.1c00513 BindingDB Entry DOI: 10.7270/Q2251P0M | |||||||||||
More data for this Ligand-Target Pair |