null
SMILES: [H][C@@]12CN(C(=O)OCC)[C@@]([H])(C[C@@H]1c1ccc(cc1)-c1cc(cc3cc(ccc13)-c1ccc(cc1)C(F)(F)F)C(=O)OCC(=O)N(C)C)C2
InChI Key:
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
5-hydroxytryptamine receptor 1D (Homo sapiens (Human)) | BDBM50584892![]() (CHEMBL5077671) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | >1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of serotonin 5HT1D receptor (unknown origin) assessed as binding constant | Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01964 BindingDB Entry DOI: 10.7270/Q2611470 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 2C (Homo sapiens) | BDBM50584892![]() (CHEMBL5077671) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | >1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of serotonin 5HT2C receptor (unknown origin) assessed as binding constant | Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01964 BindingDB Entry DOI: 10.7270/Q2611470 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sigma intracellular receptor 2 (Homo sapiens (Human)) | BDBM50584892![]() (CHEMBL5077671) | UniProtKB/SwissProt GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | 1.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of sigma 2 receptor (unknown origin) assessed as binding constant | Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01964 BindingDB Entry DOI: 10.7270/Q2611470 | |||||||||||
More data for this Ligand-Target Pair |