null
SMILES: COc1ccc(CN2C(=O)C(=O)c3cc(ccc23)S(N)(=O)=O)cc1
InChI Key:
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Carbonic anhydrase 2 (Homo sapiens (Human)) | BDBM50585424 (CHEMBL5073857) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 4.90 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of human CA2 preincubated for 15 mins by phenol red dye based stopped flow CO2 hydration assay | Citation and Details Article DOI: 10.1016/j.ejmech.2021.113997 BindingDB Entry DOI: 10.7270/Q2PV6Q80 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Carbonic anhydrase 12 (Homo sapiens (Human)) | BDBM50585424 (CHEMBL5073857) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 108 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of human CA12 preincubated for 15 mins by phenol red based stopped flow CO2 hydration assay | Citation and Details Article DOI: 10.1016/j.ejmech.2021.113997 BindingDB Entry DOI: 10.7270/Q2PV6Q80 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Carbonic anhydrase 1 (Homo sapiens (Human)) | BDBM50585424 (CHEMBL5073857) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 274 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of human CA1 preincubated for 15 mins by phenol red dye based stopped flow CO2 hydration assay | Citation and Details Article DOI: 10.1016/j.ejmech.2021.113997 BindingDB Entry DOI: 10.7270/Q2PV6Q80 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Carbonic anhydrase 9 (Homo sapiens (Human)) | BDBM50585424 (CHEMBL5073857) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 1.03E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of human CA9 preincubated for 15 mins by phenol red dye based stopped flow CO2 hydration assay | Citation and Details Article DOI: 10.1016/j.ejmech.2021.113997 BindingDB Entry DOI: 10.7270/Q2PV6Q80 | |||||||||||
More data for this Ligand-Target Pair |