null

SMILES: Fc1cccc(Cn2c3ccc(cc3[nH]c2=O)C(=O)NCc2ccccc2C(F)(F)F)c1

InChI Key:

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50586925   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Peroxisome proliferator-activated receptor gamma (Homo sapiens (Human))	BDBM50586925 (CHEMBL5071398) Show SMILES Fc1cccc(Cn2c3ccc(cc3[nH]c2=O)C(=O)NCc2ccccc2C(F)(F)F)c1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	120	n/a	n/a	n/a	n/a
TBA					Assay Description Partial agonist activity at GAL4-tagged human PPARgamma LBD expressed in HEK293T cells incubated for 12 to 14 hrs by dual-Glo luciferase assay				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01331 BindingDB Entry DOI: 10.7270/Q2T43Z05
					More data for this Ligand-Target Pair
Bifunctional epoxide hydrolase 2 (Homo sapiens (Human))	BDBM50586925 (CHEMBL5071398) Show SMILES Fc1cccc(Cn2c3ccc(cc3[nH]c2=O)C(=O)NCc2ccccc2C(F)(F)F)c1 Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	153	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of recombinant human full length sEH assessed as reduction in 6-methoxy-2-naphthaldehyde formation using PHOME as substrate preincubated f...				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01331 BindingDB Entry DOI: 10.7270/Q2T43Z05
					More data for this Ligand-Target Pair