BindingDB logo
myBDB logout

null

SMILES: Cc1c(COc2cc(OCc3cncc(c3)C#N)c3CN(CC(O)=O)CCc3c2Cl)cccc1-c1cccc(OCCCN2CC[C@@H](O)C2)c1C

InChI Key:

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 507127   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Programmed cell death protein 1 [25-167,N33K], Immunoglobulin heavy constant gamma 1 [99-330,C104S,C109S,C112S,L118I,P121S]/Programmed cell death 1 ligand 1 [18-239,H172E]


(Homo sapiens (Human))		BDBM507127
PNG
(US11046675, Example 1006)
Show SMILES Cc1c(COc2cc(OCc3cncc(c3)C#N)c3CN(CC(O)=O)CCc3c2Cl)cccc1-c1cccc(OCCCN2CC[C@@H](O)C2)c1C |r|
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
n/an/a 2n/an/an/an/an/an/a


TBA



Citation and Details

BindingDB Entry DOI: 10.7270/Q2377CVC
More data for this
Ligand-Target Pair