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SMILES: FC(F)Cn1cc(Nc2nc(N[C@H]3CN(CC[C@H]3F)C(=O)C=C)c3c(c[nH]c3n2)C#N)cn1

InChI Key:

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 511041   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase BTK (Homo sapiens (Human))	BDBM511041 (US11078206, Example 7) Show SMILES FC(F)Cn1cc(Nc2nc(N[C@H]3CN(CC[C@H]3F)C(=O)C=C)c3c(c[nH]c3n2)C#N)cn1 |r| Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	0.800	n/a	n/a	n/a	n/a	n/a	n/a
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Tyrosine-protein kinase JAK3 (Homo sapiens (Human))	BDBM511041 (US11078206, Example 7) Show SMILES FC(F)Cn1cc(Nc2nc(N[C@H]3CN(CC[C@H]3F)C(=O)C=C)c3c(c[nH]c3n2)C#N)cn1 |r| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	0.200	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair