null
SMILES: CC(C)CN1C(=O)Cc2cc(ccc12)-c1cncc(c1)-c1ccc(=O)n(c1)C(C)C
InChI Key:
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Activin receptor type-1 [172-499] (Homo sapiens (Human)) | BDBM522116![]() (US11160797, Example 24) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | 67 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Example 53: The assays were performed in 384-well, low volume microtiter assay plates in a final reaction volume of 6 ul. Dose-response curves were g... | Citation and Details BindingDB Entry DOI: 10.7270/Q2M048M3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Bone morphogenetic protein receptor type-1A [198-525] (Homo sapiens (Human)) | BDBM522116![]() (US11160797, Example 24) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | 300 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Example 53: The assays were performed in 384-well, low volume microtiter assay plates in a final reaction volume of 6 ul. Dose-response curves were g... | Citation and Details BindingDB Entry DOI: 10.7270/Q2M048M3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Activin receptor type-1 [172-499] (Homo sapiens (Human)) | BDBM522116![]() (US11160797, Example 24) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | 70 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Example 54:The assays were performed in 384-well, low volume microtiter assay plates in a final reaction volume of 9 ul. Dose-response curves were ge... | Citation and Details BindingDB Entry DOI: 10.7270/Q2M048M3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Bone morphogenetic protein receptor type-1B [168-495] (Homo sapiens (Human)) | BDBM522116![]() (US11160797, Example 24) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | 800 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Example 54:The assays were performed in 384-well, low volume microtiter assay plates in a final reaction volume of 9 ul. Dose-response curves were ge... | Citation and Details BindingDB Entry DOI: 10.7270/Q2M048M3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serine/threonine-protein kinase receptor R3 [166-493] (Homo sapiens (Human)) | BDBM522116![]() (US11160797, Example 24) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | 420 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Example 54:The assays were performed in 384-well, low volume microtiter assay plates in a final reaction volume of 9 ul. Dose-response curves were ge... | Citation and Details BindingDB Entry DOI: 10.7270/Q2M048M3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
TGF-beta receptor type-1 [162-503] (Homo sapiens (Human)) | BDBM522116![]() (US11160797, Example 24) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.90E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Example 54:The assays were performed in 384-well, low volume microtiter assay plates in a final reaction volume of 9 ul. Dose-response curves were ge... | Citation and Details BindingDB Entry DOI: 10.7270/Q2M048M3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Activin receptor type-1 [172-499,R206H] (Homo sapiens (Human)) | BDBM522116![]() (US11160797, Example 24) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | 60 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Example 54:The assays were performed in 384-well, low volume microtiter assay plates in a final reaction volume of 9 ul. Dose-response curves were ge... | Citation and Details BindingDB Entry DOI: 10.7270/Q2M048M3 | |||||||||||
More data for this Ligand-Target Pair |