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SMILES: C[C@H]1CN(Cc2ccc(F)c(c2)-c2ccc(N3CCN(C)CC3)c(NC(=O)c3c[nH]c(=O)cc3C(F)(F)F)c2)C[C@@H](C)O1

InChI Key:

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 525583   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
P61964[22-334]/Q03164[3745-3969]/Q15291/Q9C005/Q9UBL3[2-534] (Human-Homo sapiens (Human))	BDBM525583 (US11174250, Example 1) Show SMILES C[C@H]1CN(Cc2ccc(F)c(c2)-c2ccc(N3CCN(C)CC3)c(NC(=O)c3c[nH]c(=O)cc3C(F)(F)F)c2)C[C@@H](C)O1 |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	764	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Compound potency was assessed through incorporation of 3H-SAM into oligonucleosomes purified from HeLa cells. Specifically, recombinant human MLL1 (a...				Citation and Details BindingDB Entry DOI: 10.7270/Q2C53Q0K
					More data for this Ligand-Target Pair
WD repeat-containing protein 5 (Homo sapiens (Human))	BDBM525583 (US11174250, Example 1) Show SMILES C[C@H]1CN(Cc2ccc(F)c(c2)-c2ccc(N3CCN(C)CC3)c(NC(=O)c3c[nH]c(=O)cc3C(F)(F)F)c2)C[C@@H](C)O1 |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	17	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Exemplary compounds of the application were dissolved in 100% DMSO at 10 mM, assayed fresh, and then stored at −20° C. for repeat studies and o...				Citation and Details BindingDB Entry DOI: 10.7270/Q2C53Q0K
					More data for this Ligand-Target Pair