null
SMILES: C[C@@H]1CN(c2cc(ncc2C(=O)NS(=O)(=O)c2ccccc2)-n2ccc(OCCC3(CC3)C(F)(F)F)n2)C(C)(C)C1
InChI Key:
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Cystic fibrosis transmembrane conductance regulator [1-507,509-1480] (Homo sapiens (Human)) | BDBM526505 (US11186566, Compound 44) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 620 | n/a | n/a | n/a | n/a |
TBA | Assay Description The assay utilizes fluorescent voltage sensing dyes to measure changes in membrane potential using a fluorescent plate reader (e.g., FLIPR III, Molec... | Citation and Details BindingDB Entry DOI: 10.7270/Q22R3VVH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cystic fibrosis transmembrane conductance regulator [1-507,509-1480] (Homo sapiens (Human)) | BDBM526505 (US11186566, Compound 44) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 550 | n/a | n/a | n/a | n/a |
TBA | Assay Description The assay utilizes fluorescent voltage sensing dyes to measure changes in membrane potential using a fluorescent plate reader (e.g., FLIPR III, Molec... | Citation and Details BindingDB Entry DOI: 10.7270/Q22R3VVH | |||||||||||
More data for this Ligand-Target Pair |