BDBM52755 MLS001004059::N-[2-(2-cyano-4-nitro-anilino)ethyl]acetamide::N-[2-(2-cyano-4-nitroanilino)ethyl]acetamide::N-[2-[(2-cyano-4-nitro-phenyl)amino]ethyl]ethanamide::SMR000377772::cid_4841766

SMILES: CC(=O)NCCNc1ccc(cc1C#N)[N+]([O-])=O

InChI Key: InChIKey=SVGLHBXJLVCYTC-UHFFFAOYSA-N

Data: 3 IC50  2 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 52755   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
POsterior Segregation family member (pos-1) (Caenorhabditis elegans)	BDBM52755 (MLS001004059 | N-[2-(2-cyano-4-nitro-anilino)ethyl...) Show SMILES CC(=O)NCCNc1ccc(cc1C#N)[N+]([O-])=O Show InChI InChI=1S/C11H12N4O3/c1-8(16)13-4-5-14-11-3-2-10(15(17)18)6-9(11)7-12/h2-3,6,14H,4-5H2,1H3,(H,13,16)	PDB KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	n/a	n/a	3.00E+5	n/a	n/a	n/a	n/a
Broad Institute Curated by PubChem BioAssay					Assay Description Broad Institute: MLPCN maternal gene expression Project ID: 2024 Keywords: Zinc finger, C. elegans, maternal gene expression, RNA-protein interac...				PubChem Bioassay (2009) BindingDB Entry DOI: 10.7270/Q28G8J4C
					More data for this Ligand-Target Pair
RecName: Full=Zinc finger protein mex-5 (Caenorhabditis elegans)	BDBM52755 (MLS001004059 | N-[2-(2-cyano-4-nitro-anilino)ethyl...) Show SMILES CC(=O)NCCNc1ccc(cc1C#N)[N+]([O-])=O Show InChI InChI=1S/C11H12N4O3/c1-8(16)13-4-5-14-11-3-2-10(15(17)18)6-9(11)7-12/h2-3,6,14H,4-5H2,1H3,(H,13,16)	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	n/a	n/a	3.00E+5	n/a	n/a	n/a	n/a
Broad Institute Curated by PubChem BioAssay					Assay Description Broad Institute: MLPCN maternal gene expression Project ID: 2024 Keywords: Zinc finger, C. elegans, maternal gene expression, RNA-protein interac...				PubChem Bioassay (2009) BindingDB Entry DOI: 10.7270/Q2D798VP
					More data for this Ligand-Target Pair
Aurora kinase B (Homo sapiens (Human))	BDBM52755 (MLS001004059 | N-[2-(2-cyano-4-nitro-anilino)ethyl...) Show SMILES CC(=O)NCCNc1ccc(cc1C#N)[N+]([O-])=O Show InChI InChI=1S/C11H12N4O3/c1-8(16)13-4-5-14-11-3-2-10(15(17)18)6-9(11)7-12/h2-3,6,14H,4-5H2,1H3,(H,13,16)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	141	n/a	n/a	n/a	n/a	n/a	n/a
Fudan University Curated by ChEMBL					Assay Description Inhibition of recombinant Aurora B kinase (unknown origin) expressed in Escherichia coli				Eur J Med Chem 65: 151-7 (2013) Article DOI: 10.1016/j.ejmech.2013.04.058 BindingDB Entry DOI: 10.7270/Q2C82BQ3
					More data for this Ligand-Target Pair
Aurora kinase A (Homo sapiens (Human))	BDBM52755 (MLS001004059 | N-[2-(2-cyano-4-nitro-anilino)ethyl...) Show SMILES CC(=O)NCCNc1ccc(cc1C#N)[N+]([O-])=O Show InChI InChI=1S/C11H12N4O3/c1-8(16)13-4-5-14-11-3-2-10(15(17)18)6-9(11)7-12/h2-3,6,14H,4-5H2,1H3,(H,13,16)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.60	n/a	n/a	n/a	n/a	n/a	n/a
Fudan University Curated by ChEMBL					Assay Description Inhibition of Aurora A kinase (unknown origin) by Z'-LYTE kinase assay				Eur J Med Chem 65: 151-7 (2013) Article DOI: 10.1016/j.ejmech.2013.04.058 BindingDB Entry DOI: 10.7270/Q2C82BQ3
					More data for this Ligand-Target Pair
Aurora kinase B (Homo sapiens (Human))	BDBM52755 (MLS001004059 | N-[2-(2-cyano-4-nitro-anilino)ethyl...) Show SMILES CC(=O)NCCNc1ccc(cc1C#N)[N+]([O-])=O Show InChI InChI=1S/C11H12N4O3/c1-8(16)13-4-5-14-11-3-2-10(15(17)18)6-9(11)7-12/h2-3,6,14H,4-5H2,1H3,(H,13,16)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.70	n/a	n/a	n/a	n/a	n/a	n/a
Fudan University Curated by ChEMBL					Assay Description Inhibition of Aurora B kinase (unknown origin) by Z'-LYTE kinase assay				Eur J Med Chem 65: 151-7 (2013) Article DOI: 10.1016/j.ejmech.2013.04.058 BindingDB Entry DOI: 10.7270/Q2C82BQ3
					More data for this Ligand-Target Pair