null

SMILES: CO[C@H]1CC[C@@H](CC1)Nc1ncc2C[C@@H](C)N(Cc2n1)C(=O)[C@H]1CCN(C)C[C@@H]1c1ccccc1

InChI Key:

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 530260   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7 (Homo sapiens (Human))	BDBM530260 (WO2022064009, Compound 37) Show SMILES CO[C@H]1CC[C@@H](CC1)Nc1ncc2C[C@@H](C)N(Cc2n1)C(=O)[C@H]1CCN(C)C[C@@H]1c1ccccc1 |r,wU:28.32,14.15,5.8,wD:22.24,2.1,(6.42,-7.66,;5.09,-6.89,;3.75,-7.66,;2.42,-6.89,;1.08,-7.66,;1.08,-9.2,;2.42,-9.97,;3.75,-9.2,;-.25,-9.97,;-1.58,-9.2,;-2.92,-9.97,;-4.25,-9.2,;-4.25,-7.66,;-5.58,-6.89,;-5.58,-5.35,;-6.92,-4.58,;-4.25,-4.58,;-2.92,-5.35,;-2.92,-6.89,;-1.58,-7.66,;-4.25,-3.04,;-5.58,-2.27,;-2.92,-2.27,;-1.58,-3.04,;-.25,-2.27,;-.25,-.73,;1.08,.04,;-1.58,.04,;-2.92,-.73,;-4.25,.04,;-4.25,1.58,;-5.58,2.35,;-6.92,1.58,;-6.92,.04,;-5.58,-.73,)| Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	2.51	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details BindingDB Entry DOI: 10.7270/Q2MC936B
					More data for this Ligand-Target Pair
CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7 (Homo sapiens (Human))	BDBM530260 (WO2022064009, Compound 37) Show SMILES CO[C@H]1CC[C@@H](CC1)Nc1ncc2C[C@@H](C)N(Cc2n1)C(=O)[C@H]1CCN(C)C[C@@H]1c1ccccc1 |r,wU:28.32,14.15,5.8,wD:22.24,2.1,(6.42,-7.66,;5.09,-6.89,;3.75,-7.66,;2.42,-6.89,;1.08,-7.66,;1.08,-9.2,;2.42,-9.97,;3.75,-9.2,;-.25,-9.97,;-1.58,-9.2,;-2.92,-9.97,;-4.25,-9.2,;-4.25,-7.66,;-5.58,-6.89,;-5.58,-5.35,;-6.92,-4.58,;-4.25,-4.58,;-2.92,-5.35,;-2.92,-6.89,;-1.58,-7.66,;-4.25,-3.04,;-5.58,-2.27,;-2.92,-2.27,;-1.58,-3.04,;-.25,-2.27,;-.25,-.73,;1.08,.04,;-1.58,.04,;-2.92,-.73,;-4.25,.04,;-4.25,1.58,;-5.58,2.35,;-6.92,1.58,;-6.92,.04,;-5.58,-.73,)| Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	9.77	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details BindingDB Entry DOI: 10.7270/Q2MC936B
					More data for this Ligand-Target Pair