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SMILES: Cc1c(F)c(F)c(cc1C(=O)NCC(F)(F)[C@H](O)c1ccc(F)cc1)-c1ccn2nc(N)nc2c1

InChI Key:

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 534380   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM534380 (5-(2-amino-[1,2,4]triazolo[1,5-α]pyridin-7-yl...) Show SMILES Cc1c(F)c(F)c(cc1C(=O)NCC(F)(F)[C@H](O)c1ccc(F)cc1)-c1ccn2nc(N)nc2c1 |r| Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	WIPO WO2022086828	n/a	n/a	>1.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description A solution was prepared containing 0.2 nM Anti GST-Tb (Cisbio, 61GSTTLB), 40 nM probe and 1 nM GST-tagged PIK3C5 in complex with PIK3R1 (Invitrogen #...				Citation and Details BindingDB Entry DOI: 10.7270/Q2M32ZZ4
					More data for this Ligand-Target Pair
Receptor-interacting serine/threonine-protein kinase 1 (Homo sapiens (Human))	BDBM534380 (5-(2-amino-[1,2,4]triazolo[1,5-α]pyridin-7-yl...) Show SMILES Cc1c(F)c(F)c(cc1C(=O)NCC(F)(F)[C@H](O)c1ccc(F)cc1)-c1ccn2nc(N)nc2c1 |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	WIPO WO2022086828	n/a	n/a	0.400	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description A solution was prepared containing 0.2 nM Anti GST-Tb (Cisbio, 61GSTTLB), 90.6 nM probe and 1 nM His-GST-TVMV-hRIPKl (1-324) in FRET Buffer (20 mM HE...				Citation and Details BindingDB Entry DOI: 10.7270/Q2M32ZZ4
					More data for this Ligand-Target Pair