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SMILES: O[C@H](C1CCC(CC1)c1ccccc1)c1c(sc2cncn12)C1CC1

InChI Key:

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 541862   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tryptophan 2,3-dioxygenase (Homo sapiens (Human))	BDBM541862 (US11267824, Example 73a) Show SMILES O[C@H](C1CCC(CC1)c1ccccc1)c1c(sc2cncn12)C1CC1 |r,wD:1.0,(.55,-5.1,;-.48,-3.96,;-1.98,-4.28,;-2.46,-5.74,;-3.96,-6.06,;-4.99,-4.92,;-4.52,-3.45,;-3.01,-3.13,;-6.5,-5.24,;-6.98,-6.7,;-8.48,-7.02,;-9.51,-5.88,;-9.04,-4.41,;-7.53,-4.09,;,-2.49,;-.91,-1.25,;;1.46,-.48,;2.93,,;3.83,-1.25,;2.93,-2.49,;1.46,-2.02,;-2.45,-1.25,;-3.78,-2.02,;-3.78,-.48,)| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description TDO2: Recombinant human TDO comprising amino acids 19-407 with a N-terminal hexahistidine tag expressed in E. coli and purified to homogeneity is inc...				Citation and Details BindingDB Entry DOI: 10.7270/Q2RB77T6
					More data for this Ligand-Target Pair
Indoleamine 2,3-dioxygenase 1 (Homo sapiens (Human))	BDBM541862 (US11267824, Example 73a) Show SMILES O[C@H](C1CCC(CC1)c1ccccc1)c1c(sc2cncn12)C1CC1 |r,wD:1.0,(.55,-5.1,;-.48,-3.96,;-1.98,-4.28,;-2.46,-5.74,;-3.96,-6.06,;-4.99,-4.92,;-4.52,-3.45,;-3.01,-3.13,;-6.5,-5.24,;-6.98,-6.7,;-8.48,-7.02,;-9.51,-5.88,;-9.04,-4.41,;-7.53,-4.09,;,-2.49,;-.91,-1.25,;;1.46,-.48,;2.93,,;3.83,-1.25,;2.93,-2.49,;1.46,-2.02,;-2.45,-1.25,;-3.78,-2.02,;-3.78,-.48,)| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	6.45	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description IDO1: Recombinant full-length human IDO1 with a N-terminal hexahistidine tag expressed in E. coli and purified to homogeneity is incubated at a final...				Citation and Details BindingDB Entry DOI: 10.7270/Q2RB77T6
					More data for this Ligand-Target Pair