null
SMILES: CS(=O)(=O)NC(Cc1nc[nH]c(=O)c1O)c1ccc(cc1)C#Cc1ccc(CN2CCOCC2)cc1
InChI Key:
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
UDP-3-O-acyl-N-acetylglucosamine deacetylase (Escherichia coli) | BDBM563294 (US11407740, Compound 289) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | <10 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description IC50 values against E. coli LpxC were determined using a Rapid Fire MS assay as previously described J. Med. Chem. 2012, 55, 1662-1670. | Citation and Details BindingDB Entry DOI: 10.7270/Q2GM8BH2 | |||||||||||
More data for this Ligand-Target Pair |