null
SMILES: Cc1cc(cnc1C(=O)Nc1ccc2[nH]nc(-c3ccc(cc3)C(=O)N3CCOCC3)c2c1)C#N
InChI Key:
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Leucine-rich repeat serine/threonine-protein kinase 2 [G2019S] (Homo sapiens (Human)) | BDBM568961 (5-cyano-3-methyl-N-(3-(4- (morpholine-4- carbonyl...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description The assay was carried out under the following protocol conditions: 1 mM compound in DMSO was serially diluted 1:3, 11 points in DMSO with a Biomek FX... | Citation and Details BindingDB Entry DOI: 10.7270/Q2XG9VCH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Leucine-rich repeat serine/threonine-protein kinase 2 (Homo sapiens (Human)) | BDBM568961 (5-cyano-3-methyl-N-(3-(4- (morpholine-4- carbonyl...) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 550 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description The assay was carried out under the following protocol conditions: 1 mM compound in DMSO was serially diluted 1:3, 11 points in DMSO with a Biomek FX... | Citation and Details BindingDB Entry DOI: 10.7270/Q2XG9VCH | |||||||||||
More data for this Ligand-Target Pair |